Chemical compounds from anthropogenic environment and immune evasion mechanisms: potential interactions A Ternary Mixture of Common Chemicals Perturbs Benign Human Breast Epithelial Cells More Than the Same Chemicals Do Individually
Search results for "hallmarks"
Therapies targeting Hallmarks of Cancer
The modulatory role of low concentrations of bisphenol A on tamoxifen-induced proliferation and apoptosis in breast cancer cells <a href=”https://www-sciencedirect-com.ucsf.idm.oclc.org/science/article/pii/S0734975017301544″>Bisphenol A (BPA) and cell signaling pathways – drug resistrance</a> 01 – Bisphenol uncontrolled cell growth proliferation <a href=”https://www-sciencedirect-com.ucsf.idm.oclc.org/science/article/pii/S1044579X17300172″>Targeting miRNAs by polyphenols: Novel therapeutic strategy for cancer</a> 01, 03, 10,Naringenin inhibits proliferation, migration, and invasion as […]
Chemical Company advocates attack use of Hallmarks and Key Characteristics of Cancer
Application of the key characteristics of carcinogens in cancer hazard identification Letter to the editor re: Guyton et al. (2018), ‘Application of the key characteristics of carcinogens in cancer hazard identification’ Re: ‘Application of the key characteristics of carcinogens in cancer hazard evaluation’: response to Goodman, Lynch and Rhomberg
The Hallmarks of Cancer in a Nutshell
The “Hallmarks of Cancer” were described for the first time in 2008 (and updated in 2011), as the subject of a landmark paper written by research scientists Douglas Hanahan and Robert A. Weinberg and published in the prestigious scientific journal Cell. The 2008 “Hallmarks of Cancer” paper defined six rules of interlocking processes that fed […]
Wrong Paradigm, Wrong Conclusion
I had a winter mountaineering and ice climbing buddy who died of gastric cancer at age 30. He was a former Army combat medic and veteran of multiple tours in Iraq. At the very end of December 2012 we were attempting a summit of the California Matterhorn in the Eastern Sierra. That didn’t slowdown his […]
Your cells: Complicated, vulnerable to disruption by BPA and other chemicals
Complicated and Fragile Another reason that such small concentrations can affect you is that they operate inside of tiny cells that are complicated and fragile. And that makes it a matter both of scale and potency. The cells in your body are like a well-run city maintained with carefully balanced mechanisms that produce energy, get […]
Why “Cancer Powerball?” What’s the reasoning and science behind it?
This article is part of the introductory series on Cancer Powerball. Cancer Powerball: The lottery where you lose every time you win Bisphenol A (BPA) Pre-checks ALL 10 Numbers on your “Winning” Cancer Powerball ticket It took six years of racking my brain and scouring the scientific literature to invent an easily understandable, science-based way […]
Bisphenol A (BPA) Pre-checks ALL 10 Numbers on your “Winning” Cancer Powerball ticket
Bisphenol A can give you an instant “win” because it can check off all 10 Cancer Powerball numbers PLUS it hinders the effectiveness of cancer treatment drugs/chemotherapy. This article is one of a new series to help intelligent non-scientists understand the confusing probabilities of how chemicals, genetics, radiation and other factors can cause cancer. It’s […]
Reprogramming Cellular Metabolism
Cell Metabolism Fundamentals of cancer metabolism From: Fundamentals of cancer metabolism The Emerging Hallmarks of Cancer Metabolism Modeling the Genetic Regulation of Cancer Metabolism: Interplay between Glycolysis and Oxidative Phosphorylation
Cancer Powerball: The lottery where you lose every time you win
Getting cancer can be a lot like playing Powerball with your health and mortality. Like Powerball, you need to get all 10 to “win.” This article is #1 in a new way to help intelligent non-scientists understand the confusing probabilities of how chemicals, genetics, radiation and other factors can cause cancer. It’s vital to understand […]